Anagathics

Anagathics is the science of life prolongation; it delves into the significant extension of human lifespan and the delay of the onset of age-related diseases. It harnesses advanced biochemistry and molecular medicine to enhance - perhaps even nullify - the biological ageing process.

Several aspects characterise this field:

• Telomere maintenance: usage of compounds that target and stabilise telomeres - protective caps at the ends of chromosomes that shorten with each cell division. By preserving telomere length, such drugs effectively reduce cellular ageing and improve longevity.
• Cellular senescence inhibition: agents are designed to inhibit pathways involved in cellular senescence, a state where cells lose their ability to divide and function properly. By suppressing the markers of senescence, anagathics help maintain cellular health and functionality.
• Mitochondrial optimisation: inclusion of components that enhance mitochondrial function, which is crucial for energy production and cellular repair.
• Proteostasis regulation: regulatation of the balance of protein synthesis, folding, and degradation within cells. By ensuring proper proteostasis, drugs prevent the accumulation of damaged or misfolded proteins, which is associated with many age-related symptoms.
• Genomic stability enhancement: pathways are targeted to maintain genomic integrity, reducing the incidence of mutations and chromosomal abnormalities that contribute to ageing and age-related pathologies.